Preparation and Characterization and Biodistribution Studies of Lomustine Loaded PLGA Nanoparticles by Interfacial Deposition Method
نویسندگان
چکیده
منابع مشابه
Preparation of protein-loaded PLGA-PVP blend nanoparticles by nanoprecipitation method: entrapment, Initial burst and drug release kinetic studies
Objective(s):Despite of wide range applications of polymeric nanoparticles in protein delivery, there are some problems for the field of protein entrapment, initial burst and controlled release profile. Materials and Methods: In this study, we investigated the influence of some changes in PLGA nanoparticles formulation to improve the initial and controlled release profile. Selected parameters ...
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The purpose of this study was to prepare and characterize microspheres loaded by cyclosporine A(CyA)-cyclodextrin (CD) complex. To achieve this goal, PLGA microspheres loaded by CyA CD complex were prepared by multiple emulsificationsolvent evaporation methods.Morphology, size, encapsulation efficiency and drug release from these microspheres were evaluated. Microscopic evaluation of mi...
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objective(s):despite of wide range applications of polymeric nanoparticles in protein delivery, there are some problems for the field of protein entrapment, initial burst and controlled release profile. materials and methods: in this study, we investigated the influence of some changes in plga nanoparticles formulation to improve the initial and controlled release profile. selected parameters ...
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Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer types. There are important matters of concern regarding the drug's pharmacokinetics related to the conventional formulation. Poly(lactide-co-glycolide) (PLGA) is a biocompatible/biodegradable polymer with variable physicochemical characteristics, and its application in human has been approved by the United Sta...
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Background and objectives: Tribulus terrestris is a flowering herb (Zygophyllaceae) with several properties in folk medicine such as diuretic, tonic, aphrodisiac, analgesic, astringent, and stomachic-lithotripter activities. Although, some extracts and phytochemicals represent excellent bio-activity in vitro, less or no in vivo activity is observed du...
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ژورنال
عنوان ژورنال: Journal of Nanomedicine & Nanotechnology
سال: 2015
ISSN: 2157-7439
DOI: 10.4172/2157-7439.1000328